Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Epilepsy

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 0 · 0%Moderate 1 · 33.3%High 1 · 33.3%

All‐cause mortality · people with traumatic head injuries

Anti‐epileptic drugs showed no clear difference in all‐cause mortality compared with other anti‐epileptic drugs (moderate certainty).

1 finding from 1 review

Pharmacological treatments for preventing epilepsy following traumatic head injury 2015 · Cochrane Headline outcomes only
RR 0.53 [0.3, 94]
2 studies · 431 participants
Moderate

All‐cause mortality · people with traumatic head injuries

It is very uncertain whether antiepileptic drugs changes all‐cause mortality compared with placebo or standard care (very low certainty).

1 finding from 1 review

Pharmacological treatments for preventing epilepsy following traumatic head injury 2015 · Cochrane Headline outcomes only
RR 1.08 [0.79, 1.46]
5 studies · 1065 participants
Very low

All‐cause mortality · people with traumatic head injuries

Neuroprotective agent showed no clear difference in all‐cause mortality compared with placebo (high certainty).

1 finding from 1 review

Pharmacological treatments for preventing epilepsy following traumatic head injury 2015 · Cochrane Headline outcomes only
RR 1.2 [0.8, 1.81]
1 study · 466 participants
High