Findings

What do systematic reviews say?

6 questions · 8 findings · 2 reviews

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No studies found 4 · 50%GRADE not reported 0 · 0%Very low 1 · 12.5%Low 2 · 25%Moderate 1 · 12.5%High 0 · 0%

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs standard treatment following a severe exacerbation

All‐cause mortality · post‐exacerbation COPD

Summary of Findings Table ‐ Chronic non‐invasive ventilation showed no clear difference in all‐cause mortality compared with standard treatment following a severe exacerbation (low certainty).

1 finding from 1 review

Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
HR 0.97 [0.74, 1.28]
2 studies · 318 participants
Low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs usual care

All‐cause mortality · stable COPD

Summary of Findings Table ‐ Chronic non‐invasive ventilation probably leads to lower all‐cause mortality compared with standard treatment (moderate certainty).

1 finding from 1 review

Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
HR 0.75 [0.58, 0.97]
3 studies · 405 participants
Moderate

Adaptive servo ventilation (ASV) vs bilevel ventilation

All‐cause mortality

The review found no eligible studies for this question.

2 findings from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP)

All‐cause mortality

The review found no eligible studies for this question.

2 findings from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

All‐cause mortality ‐ up to 80 months Number of participants: 1355(2 RCTs)

Adaptive servo ventilation (ASV) plus best supportive care showed no clear difference in all‐cause mortality ‐ up to 80 months Number of participants: 1355(2… compared with best supportive care alone or inactive control (low certainty).

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
RR 0.56 [0.06, 4.93]
Studies not reported
Low

Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care

All‐cause mortality ‐ after 24 months Number of participants: 287(2 RCTs)

It is very uncertain whether continuous positive airway pressure (CPAP) plus best supportive care changes all‐cause mortality ‐ after 24 months Number of participants: 287(2… compared with best supportive care (very low certainty).

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
RR 1.14 [0.83, 1.56]
Studies not reported
Very low