Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Hepato-Biliary

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%

All‐cause mortality · adult patients with non‐paracetamol (acetaminophen)‐related acute liver failure

N‐acetylcysteine showed no clear difference in all‐cause mortality compared with placebo (low certainty).

1 finding from 1 review

N‐acetylcysteine for non‐paracetamol (acetaminophen)‐related acute liver failure 2020 · Cochrane Headline outcomes only
RR 0.88 [0.57, 1.37]
1 study · 173 participants
Low

All‐cause mortality · children with non‐paracetamol (acetaminophen)‐related acute liver failure

N‐acetylcysteine showed no clear difference in all‐cause mortality compared with placebo (low certainty).

1 finding from 1 review

N‐acetylcysteine for non‐paracetamol (acetaminophen)‐related acute liver failure 2020 · Cochrane Headline outcomes only
RR 1.47 [0.85, 2.53]
1 study · 184 participants
Low