Findings

What do systematic reviews say?

5 questions · 5 findings · 3 reviews · Acute Respiratory Infections

No studies found 1 · 20%GRADE not reported 0 · 0%Very low 1 · 20%Low 0 · 0%Moderate 3 · 60%High 0 · 0%

All‐cause mortality · patients with a recent BSF independent of the presence or severity of CSF leakage

The intervention showed no clear difference in all‐cause mortality (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis for preventing meningitis in patients with basilar skull fractures 2015 · Cochrane Headline outcomes only
OR 1.68 [0.41, 6.95]
4 studies · 208 participants
Moderate

All‐cause mortality; · Ventilator‐associated pneumonia

Monotherapy showed no clear difference in all‐cause mortality; compared with combination therapy (moderate certainty).

1 finding from 1 review

Antibiotics for ventilator‐associated pneumonia 2016 · Cochrane Headline outcomes only
OR 0.97 [0.73, 1.3]
4 studies · 1163 participants
Moderate

All‐cause mortality; · Ventilator‐associated pneumonia

Carbapenems showed no clear difference in all‐cause mortality; compared with non‐carbapenems (moderate certainty).

1 finding from 1 review

Antibiotics for ventilator‐associated pneumonia 2016 · Cochrane Headline outcomes only
OR 0.59 [0.3, 1.19]
1 study · 253 participants
Moderate

All‐cause mortality maximum · neonates and children with hospital‐acquired pneumonia

It is very uncertain whether cefepime changes all‐cause mortality Maximum compared with ceftazidime (very low certainty).

1 finding from 1 review

Antibiotics for hospital‐acquired pneumonia in neonates and children 2021 · Cochrane Headline outcomes only
RR 0.14 [0.01, 2.55]
1 study · 30 participants
Very low

All‐cause mortality maximum · neonates and children with hospital‐acquired pneumonia

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for hospital‐acquired pneumonia in neonates and children 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found