Findings

What do systematic reviews say?

7 questions · 7 findings · 2 reviews · Airways

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 14.3%Low 0 · 0%Moderate 3 · 42.9%High 3 · 42.9%

Airway bypass stents vs control

Adverse events at end of · patients with chronic obstructive pulmonary disease

Airway bypass stents showed no clear difference in adverse events at end of compared with control (moderate certainty).

1 finding from 1 review

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
OR 1.33 [0.65, 2.73]
1 study · 315 participants
Moderate

Endobronchial coils vs control

Adverse events at end of · patients with chronic obstructive pulmonary disease

Endobronchial coils leads to higher adverse events at end of compared with control (high certainty).

1 finding from 1 review

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
OR 2.14 [1.41, 3.23]
3 studies · 461 participants
High

Endobronchial valves vs control

Adverse events at end of · patients with chronic obstructive pulmonary disease

Endobronchial valves leads to higher adverse events at end of compared with control (high certainty).

1 finding from 1 review

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
OR 5.85 [2.16, 15.84]
3 studies · 482 participants
High

Intrabronchial valves vs control

Adverse events at end of · patients with chronic obstructive pulmonary disease

Intrabronchial valves leads to higher adverse events at end of compared with control (high certainty).

1 finding from 1 review

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
OR 3.41 [1.48, 7.84]
2 studies · 350 participants
High

Vapour ablation vs control

Adverse events at end of · patients with chronic obstructive pulmonary disease

Vapour ablation showed no clear difference in adverse events at end of compared with control (moderate certainty).

1 finding from 1 review

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
OR 3.86 [1, 14.97]
1 study · 69 participants
Moderate

AeriSeal vs control

Adverse events at end of · patients with chronic obstructive pulmonary disease

AeriSeal probably leads to higher adverse events at end of compared with control (moderate certainty).

1 finding from 1 review

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
OR 3.71 [1.34, 10.24]
1 study · 95 participants
Moderate

Macrolide+tetracycline vs macrolides

All‐cause serious adverse events 60 weeks (end of study) · patients with chronic obstructive pulmonary disease

It is very uncertain whether macrolide+tetracycline changes all‐cause serious adverse events 60 weeks (end of study) compared with macrolide (very low certainty).

1 finding from 1 review

Head‐to‐head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
OR 1 [0.52, 1.93]
1 study · 198 participants
Very low