Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Neonatal

No studies found 1 · 33.3%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%

Adverse events (treatment related) To discharge · newborn infants with opioid withdrawal

Morphine showed no clear difference in adverse events (treatment related) To discharge compared with methadone (low certainty).

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
RR 0.33 [0.01, 8.02]
1 study · 116 participants
Low

Adverse events (treatment related) To discharge · newborn infants with opioid withdrawal

It is very uncertain whether morphine changes adverse events (treatment‐related) To discharge compared with buprenorphine (very low certainty).

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
RR 0.33 [0.01, 7.5]
3 studies · 113 participants
Very low

Adverse events (treatment related) To discharge · newborn infants with opioid withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found