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Evidence found and GRADE certainty

2 questions · 4 findings · 2 reviews

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Intraglandular botulinum neurotoxin (BoNT) injection vs placebo injection

Adverse events (participants with >=1 adverse event) · Adults with Parkinson's disease and sialorrhea (drooling)

Type A botulinum toxin showed a borderline, non-significant increase in adverse events versus placebo (RD 0.10, 95% CI 0.00 to 0.21; ungraded subgroup).

3 findings from 1 review

Live zoster vaccine vs placebo

Participants with adverse events ‐ injection site adverse events Clinical criteria · healthy older adults aged ≥ 60 years

Live zoster vaccine probably leads to higher participants with adverse events ‐ injection site adverse… compared with placebo (moderate certainty).

1 finding from 1 review