Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 20%Low 2 · 40%Moderate 2 · 40%High 0 · 0%

Adverse events (participants) · people with critical limb ischaemia

It is very uncertain whether prostanoids changes adverse events (participants) compared with pentoxifylline (very low certainty).

1 finding from 1 review

Prostanoids for critical limb ischaemia 2018 · Cochrane Headline outcomes only
RR 0.6 [0.24, 1.47]
1 study · 70 participants
Very low

Adverse events (participants) · people with critical limb ischaemia

Prostanoids showed no clear difference in adverse events (participants) compared with naftidrofuryl (low certainty).

1 finding from 1 review

Prostanoids for critical limb ischaemia 2018 · Cochrane Headline outcomes only
RR 3.29 [0.27, 40.19]
2 studies · 55 participants
Low

Adverse events (participants) · people with critical limb ischaemia

Prostanoids probably leads to higher adverse events (participants) compared with placebo (moderate certainty).

1 finding from 1 review

Prostanoids for critical limb ischaemia 2018 · Cochrane Headline outcomes only
RR 2.11 [1.79, 2.5]
8 studies · 655 participants
Moderate

Adverse events (participants) · people with critical limb ischaemia

PGE1 showed no clear difference in adverse events (participants) compared with inositol niacinate (low certainty).

1 finding from 1 review

Prostanoids for critical limb ischaemia 2018 · Cochrane Headline outcomes only
RR 1.6 [0.79, 3.23]
1 study · 65 participants
Low

Adverse events (participants) · people with critical limb ischaemia

Iloprost probably leads to higher adverse events (participants) compared with PGE1 (moderate certainty).

1 finding from 1 review

Prostanoids for critical limb ischaemia 2018 · Cochrane Headline outcomes only
RR 2.35 [1.82, 3.04]
4 studies · 511 participants
Moderate