Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3 questions · 3 findings · 1 reviews · Airways

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 66.7%High 1 · 33.3%

Fixed‐dose combination aclidinium/formoterol vs formoterol

Adverse events (not including serious adverse events): number of participants · patients with chronic obstructive pulmonary disease

Fixed‐dose combination aclidinium/formoterol leads to lower adverse events (not including serious adverse events): number of… compared with formoterol (high certainty).

1 finding from 1 review

Fixed‐dose combination aclidinium/formoterol vs placebo

Adverse events (not including serious adverse events): number of participants · patients with chronic obstructive pulmonary disease

Fixed‐dose combination aclidinium/formoterol showed no clear difference in adverse events (not including serious adverse events): number of… compared with placebo (moderate certainty).

1 finding from 1 review

Fixed‐dose combination aclidinium/formoterol vs aclidinium alone

Adverse events (not including serious adverse events): number of participants · patients with chronic obstructive pulmonary disease

Fixed‐dose combination aclidinium/formoterol showed no clear difference in adverse events (not including serious adverse events): number of… compared with aclidinium alone (moderate certainty).

1 finding from 1 review