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What do systematic reviews say?

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Evidence found and GRADE certainty

1,004 questions · 1,019 findings · 269 reviews

No studies found 333 · 32.7%GRADE not reported 106 · 10.4%Very low 313 · 30.7%Low 189 · 18.5%Moderate 66 · 6.5%High 12 · 1.2%

Prophylactic perindopril (2 mg to 4 mg daily) vs placebo

Adverse events · boys with DMD, normal cardiac examination and LVEF > 55% at baseline

Prophylactic perindopril (2 mg to 4 mg daily) showed no clear difference in adverse events compared with placebo (low certainty).

1 finding from 1 review