Findings

What do systematic reviews say?

1,041 questions · 1,056 findings · 283 reviews

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No studies found 346 · 32.8%GRADE not reported 111 · 10.5%Very low 326 · 30.9%Low 195 · 18.5%Moderate 66 · 6.3%High 12 · 1.1%

Ravulizumab vs placebo or alternative treatment

Adverse events · adults with aHUS

1 finding from 1 review

Interventions for atypical haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
58 participants
Very low

Eculizumab vs placebo or alternative treatment

Adverse events · children and adults with aHUS

1 finding from 1 review

Interventions for atypical haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
100 participants
Very low

Bethanechol vs placebo

Adverse events

The review found no eligible studies for this question.

1 finding from 1 review

Postoperative interventions for preventing bladder dysfunction after radical hysterectomy in women with early‐stage… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ Interactive Social Media vs non‐interactive social media

Adverse events · adults

1 finding from 1 review

Behavioural interventions delivered through interactive social media for health behaviour change, health outcomes, and… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Synsorb Pk vs placebo

Adverse events · patients with diarrhoea due to Shiga toxin‐producing E. coli

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing diarrhoea‐associated haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Urtoxazumab (3.0 mg/kg) vs placebo

Adverse events ‐ serious · paediatric patients with diarrhoea due to Shiga toxin‐producing E. coli

Urtoxazumab (3.0 mg/kg) may leads to lower adverse events ‐ serious compared with placebo (low certainty).

1 finding from 1 review

Interventions for preventing diarrhoea‐associated haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 71 participants
Low

Antibiotics vs no treatment

Adverse events · patients with diarrhoea due to Shiga toxin‐producing E. coli

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing diarrhoea‐associated haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Urtoxazumab (1.0 mg/kg) vs placebo

Adverse events ‐ serious · paediatric patients with diarrhoea due to Shiga toxin‐producing E. coli

1 finding from 1 review

Interventions for preventing diarrhoea‐associated haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 74 participants
Low

Bovine colostrum vs placebo

Adverse events · patients with diarrhoea due to Shiga toxin‐producing E. coli

It is very uncertain whether bovine colostrum changes adverse events compared with placebo (very low certainty).

1 finding from 1 review

Interventions for preventing diarrhoea‐associated haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
RR 0.92 [0.42, 2.03]
1 study · 27 participants
Very low

Non‐vocal communication aid vs usual care with an aid

Adverse events · adults requiring an artificial airway with or without mechanical ventilator support

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to enable communication for adult patients requiring an artificial airway with or without mechanical… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Voice‐enabling communication aid vs usual care with an aid

Adverse events · adults requiring an artificial airway with or without mechanical ventilator support

1 finding from 1 review

Interventions to enable communication for adult patients requiring an artificial airway with or without mechanical… 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 50 participants
Low

Non‐vocal communication aid vs usual care without an aid

Adverse events · adults requiring an artificial airway with or without mechanical ventilator support

1 finding from 1 review

Interventions to enable communication for adult patients requiring an artificial airway with or without mechanical… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1440 participants
Low

Raloxifene vs placebo

Adverse events · postmenopausal women with osteoporosis and CKD stages 5 and 5D

1 finding from 1 review

Pharmacological interventions versus placebo, no treatment or usual care for osteoporosis in people with chronic… 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 110 participants
Very low

Any anti‐osteoporotic drugs vs placebo

Adverse events · postmenopausal women with osteoporosis and CKD stages 3‐4

Any anti‐osteoporotic drugs showed no clear difference in adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Pharmacological interventions versus placebo, no treatment or usual care for osteoporosis in people with chronic… 2021 · Cochrane Headline outcomes only
RR 0.99 [0.98, 1]
5 studies · 9054 participants
Moderate

IM erythropoietin vs oral placebo

Serious adverse events · IBD patients

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating iron deficiency anaemia in inflammatory bowel disease 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Active stimulation + other intervention vs other intervention alone

Adverse events: infection · adults with chronic pain

The review found no eligible studies for this question.

1 finding from 1 review

Implanted spinal neuromodulation interventions for chronic pain in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Active stimulation + other intervention vs other intervention alone

Adverse events: other · adults with chronic pain

The review found no eligible studies for this question.

1 finding from 1 review

Implanted spinal neuromodulation interventions for chronic pain in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Active stimulation + other intervention vs other intervention alone

Adverse events:infection · adults with chronic pain

Active stimulation + other intervention may leads to higher adverse events:infection compared with other intervention alone (low certainty).

1 finding from 1 review

Implanted spinal neuromodulation interventions for chronic pain in adults 2021 · Cochrane Headline outcomes only
RR 4.83 [1.09, 21.4]
4 studies · 548 participants
Low

Active stimulation vs Placebo (sham/placebo device)

Adverse events: infection · adults with chronic pain

The review found no eligible studies for this question.

2 findings from 1 review

Implanted spinal neuromodulation interventions for chronic pain in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Implanted spinal neuromodulation interventions for chronic pain in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Active stimulation vs Placebo (sham/placebo device)

Adverse events: other · adults with chronic pain

The review found no eligible studies for this question.

1 finding from 1 review

Implanted spinal neuromodulation interventions for chronic pain in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found