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What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 10 findings · 4 reviews · Common Mental Disorders

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No studies found 2 · 20%GRADE not reported 2 · 20%Very low 6 · 60%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Abrupt discontinuation vs continuation of long‐term antidepressants

Adverse events · participants with depressive or anxiety disorders

It is very uncertain whether abrupt discontinuation changes adverse events compared with continuation of long‐term antidepressants (very low certainty).

1 finding from 1 review

Comparison 13: SSRIs vs placebo

Dropouts due to adverse events · adults with SAnD

It is very uncertain whether comparison 13: SSRIs changes dropouts due to adverse events (long term) Post‐treatment: 1‐4 months compared with placebo (very low certainty).

1 finding from 1 review

Discontinuation by "tapering" vs usual family planning care

Adverse events · participants with depressive or anxiety disorders

It is very uncertain whether discontinuation by "tapering" changes adverse events compared with continuation (or usual care) (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

acceptability ‐ drop‐outs due to adverse events: post‐intervention · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to adverse events: post‐intervention compared with placebo (very low certainty).

1 finding from 1 review