Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

30 questions · 30 findings · 7 reviews · Neuromuscular

No studies found 6 · 20%GRADE not reported 1 · 3.3%Very low 8 · 26.7%Low 7 · 23.3%Moderate 3 · 10%High 5 · 16.7%

Intervention not reported

Adverse events · participants with relapsed or recurrent CTEV

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events · participants with neglected CTEV

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events · participants with CTEV (type of case (i.e. whether initial presentation or relapsed) not specified)
1 finding from 1 review

Intervention not reported

Adverse events · participants with CTEV at initial presentation

The intervention may leads to lower adverse events (low certainty).

1 finding from 1 review

Prophylactic perindopril (2 mg to 4 mg daily) vs placebo

Adverse events · boys with DMD, normal cardiac examination and LVEF > 55% at baseline

Prophylactic perindopril (2 mg to 4 mg daily) showed no clear difference in adverse events compared with placebo (low certainty).

1 finding from 1 review

Ascorbic acid vs placebo

Serious adverse events · people with fatigue in peripheral neuropathy

Ascorbic acid showed no clear difference in serious adverse events compared with placebo (moderate certainty).

1 finding from 1 review