What do systematic reviews say?

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

• Related · question page
  • Resin-based fissure sealant vs Fluoride varnish · Safety of sealants and fluoride varnishes (adverse events)

    Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of children and… 2020 · Cochrane All outcomes
    Five studies (Bravo 2005; Chestnutt 2017; Kalnina 2016; Liu 2012; Tagliaferro 2011) considered adverse events; participants detected and reported no adverse events.
    5 studies
    GRADE not reported
• Related · question page
  • Microinvasive techniques (resin infiltration, resin/GIC sealant, or glass ionomer varnish) vs Non-invasive measures (fluoride varnish/toothpaste, flossing, oral hygiene instruction, sham/standard of care) · Adverse events and periodontal/secondary outcomes (gingival bleeding, gingival bleeding index, visible plaque index)

    Microinvasive interventions in the management of proximal caries lesions in primary and permanent teeth- systematic… 2025 All outcomes

    Baseline and follow-up · Multiple countries (Brazil, Saudi Arabia, Netherlands, USA, Turkey, Switzerland, Germany, New Zealand, Chile, Thailand); dental clinic/community settings
    Reported narratively by 3 trials (Arthur 2018, Sarti 2020, Jorge 2019). No adverse events were attributed to microinvasive treatment. Gingival bleeding index: no significant difference in Arthur 2018 and Jorge 2019 but…
    3 studies
    GRADE not reported
• Related · question page
  • Micro-invasive treatment (proximal sealing or resin infiltration): resin sealant, glass ionomer sealant, polyurethane/adhesive patch, or resin infiltration vs Non-invasive measures (e.g. fluoride varnish, flossing/oral hygiene advice), no treatment, or placebo · Adverse events

    Micro‐invasive interventions for managing proximal dental decay in primary and permanent teeth 2015 · Cochrane All outcomes

    1 to 3 years
    The four studies that measured adverse events reported no adverse events after micro-invasive treatment (no events in either arm)
    4 studies
    GRADE not reported
• Related · question page
  • Silver diamine fluoride (SDF; 38% in most trials, 30% in three) vs Other methods (pooled: ART/glass ionomer cement, nano-silver fluoride, sodium fluoride varnish, placebo) · Adverse effects (tooth staining; soft-tissue and systemic events)

    The role of silver diamine fluoride as dental caries preventive and arresting agent: a systematic review and… 2024 All outcomes

    up to 30 months · Children/adults with dental caries; multiple countries; community/clinic care setting not clearly specified
    Black staining of arrested lesions reported in most studies; 4 studies reported mild transient events (gingival blenching/pain; diarrhea/stomachache; burning, bad taste, pain, mouth injury, dissatisfaction with…
    Studies not reported
    GRADE not reported