Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

43 questions · 46 findings · 8 reviews

No studies found 17 · 37%GRADE not reported 6 · 13%Very low 9 · 19.6%Low 7 · 15.2%Moderate 4 · 8.7%High 3 · 6.5%

Neonatal vitamin A supplementation vs control

Adverse events during first 48‐72 hours post supplementation ‐ bulging fontanelle · mortality and morbidity in term neonates

Neonatal vitamin A supplementation leads to higher adverse events during first 48‐72 hours post supplementation ‐… compared with control (high certainty).

1 finding from 1 review

Lay health worker‐ vs specialist‐led care

Adverse events ‐ death from suicide during intervention (RR > 1 denotes greater risk)Â · people with severe mental disorders

It is very uncertain whether lay health worker‐ changes adverse events ‐ death from suicide during intervention (RR > 1… compared with specialist‐led care (very low certainty).

1 finding from 1 review

Primary health professional‐ and community professional‐led interventions vs enhanced usual care

Adverse events (1 to 6 months post intervention) ‐ incidence of alcohol‐related consequences ‐ accidents (RR > 1 denotes greater risk) · adult patients with harmful or hazardous alcohol or substance use

It is very uncertain whether primary health professional‐ and community professional‐led… changes adverse events (1 to 6 months post intervention) ‐ incidence of… compared with enhanced usual care (very low certainty).

1 finding from 1 review