Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews · Vascular

No studies found 1 · 50%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

TNF‐α blockers intervention vs placebo or additional treatment

Adverse effects after treatment initiation: infections · children diagnosed with Kawasaki disease

TNF‐α blockers intervention showed no clear difference in adverse effects after treatment initiation: infections compared with placebo or additional treatment (low certainty).

1 finding from 1 review

TNF‐α blockers intervention vs placebo or additional treatment

Adverse effects after treatment initiation: injection site reactions, neutropenia, infections, demyelinating disease, heart failure, malignancy, and induction of autoimmunity. · children diagnosed with Kawasaki disease

The review found no eligible studies for this question.

1 finding from 1 review