Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 6 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Adverse effects · Infants (primary teeth)

1 finding from 1 review

Xylitol‐containing products for preventing dental caries in children and adults 2015 · Cochrane All outcomes
12 months
The authors reported that there were no adverse effects for either group. Zhan 2012.
1 study · 44 participants
GRADE not reported

Adverse effects · Children with permanent teeth (schoolchildren)

1 finding from 1 review

Xylitol‐containing products for preventing dental caries in children and adults 2015 · Cochrane All outcomes
2.5 to 3 years
Adverse effects: both studies reported that there were no adverse effects in either the xylitol or control group.
2 studies · 4216 participants
GRADE not reported

Adverse effects · Children (mixed dentition; baseline about 8 years)

1 finding from 1 review

Xylitol‐containing products for preventing dental caries in children and adults 2015 · Cochrane All outcomes
36 months
The authors reported that there were no adverse effects for either group. Honkala 2014.
1 study · 252 participants
GRADE not reported

Adverse effects (loose stools, diarrhoea) · Infants (primary teeth; baseline about 9 to 15 months)

1 finding from 1 review

Xylitol‐containing products for preventing dental caries in children and adults 2015 · Cochrane All outcomes
12 months
Adverse effects were not reported in a usable format, but the reported rates of loose stools and diarrhoea were very similar between groups. There were no serious adverse effects during the study. Milgrom 2009.
1 study · 94 participants
GRADE not reported

Adverse effects · Children (permanent teeth; baseline 8 to 10 years)

1 finding from 1 review

Xylitol‐containing products for preventing dental caries in children and adults 2015 · Cochrane All outcomes
24 months (48-month follow-up)
There were no usable data presented for adverse effects. Lenkkeri 2012.
1 study
GRADE not reported

Adverse effects (sores in the mouth, cramps, bloating, constipation, flatulence, loose stool or diarrhoea) · adults

1 finding from 1 review

Xylitol‐containing products for preventing dental caries in children and adults 2015 · Cochrane All outcomes
33 months
Patterns of adverse effects (sores in the mouth, cramps, bloating, constipation, flatulence, and loose stool or diarrhoea) were similar for both groups. Bader 2013.
1 study · 669 participants
GRADE not reported