Findings

What do systematic reviews say?

5 questions · 5 findings · 2 reviews · ENT

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No studies found 2 · 40%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 60%Moderate 0 · 0%High 0 · 0%

Antihistamines vs placebo

Adverse effects: 1. Sedation · patients with motion sickness

Antihistamines may leads to higher adverse effects: sedation Assessed by: adverse effect questionnaire… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines for motion sickness 2022 · Cochrane Headline outcomes only
RR 1.51 [1.12, 2.02]
2 studies · 190 participants
Low

Antihistamines vs placebo

Adverse effects ‐ Blurred vision No of patients with blurred vision · patients with motion sickness

Antihistamines showed no clear difference in adverse effects: blurred vision Assessed by: adverse effect… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines for motion sickness 2022 · Cochrane Headline outcomes only
RR 1.14 [0.53, 2.48]
2 studies · 190 participants
Low

Antihistamines vs placebo

Adverse effects: impaired cognition Assessed by: adverse effect questionnaire (presence or absence given numerical values) · patients with motion sickness

Antihistamines showed no clear difference in adverse effects: impaired cognition Assessed by: adverse effect… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines for motion sickness 2022 · Cochrane Headline outcomes only
RR 0.89 [0.58, 1.38]
2 studies · 190 participants
Low

Intervention not reported

Any other adverse effects · adults with Ménière's disease or syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Restriction of salt, caffeine and alcohol intake for the treatment of Ménière's disease or syndrome 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Proportion of patients with adverse effects (e.g. hyponatraemia, mood disturbance and headaches) · adults with Ménière's disease or syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Restriction of salt, caffeine and alcohol intake for the treatment of Ménière's disease or syndrome 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found