Findings

What do systematic reviews say?

64 questions · 64 findings · 9 reviews · Oral medicine and oral cancer

No studies found 2 · 3.1%GRADE not reported 33 · 51.6%Very low 27 · 42.2%Low 2 · 3.1%Moderate 0 · 0%High 0 · 0%

Adverse effects · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)

1 finding from 1 review

Interventions for managing oral submucous fibrosis 2024 · Cochrane All outcomes
Adverse effects (any): 0 in placebo vs 2 minor (flatulence and bloating); 90 (1); no GRADE rating given.
1 study · 90 participants
GRADE not reported

Adverse effects · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)

1 finding from 1 review

Interventions for managing oral submucous fibrosis 2024 · Cochrane All outcomes
Adverse effects (any): 0 placebo vs 14 minor (transient flushing and upper trunk warmness); 85 (2); no GRADE rating.
2 studies · 85 participants
GRADE not reported

Adverse effects · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)

1 finding from 1 review

Interventions for managing oral submucous fibrosis 2024 · Cochrane All outcomes
Adverse effects (any): no adverse effects reported; 25 (1); no GRADE rating.
1 study · 25 participants
GRADE not reported

Adverse effects · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
Amirchaghmaghi 2016: no adverse effects recorded in either group (low-certainty)
1 study
Low

Adverse effects · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether topical corticosteroid changes adverse effects compared with placebo (very low certainty).

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
3-9 weeks
RR 1.48 [0.48, 4.56]
3 studies · 88 participants
Very low

Adverse effects · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

1 finding from 1 review

Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy 2017 · Cochrane All outcomes
No evidence of a difference in reported adverse events across the three trials (nausea, fever, constipation, diarrhoea, headache, fatigue and others)
3 studies
GRADE not reported

Adverse effects · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

1 finding from 1 review

Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomes
short-term (up to 3 months) · benzydamine hydrochloride
SoF9. Adverse effects: single study narratively reported that no adverse effects occurred from benzydamine hydrochloride oral rinse; 20 participants (1 RCT); very low.
1 study · 20 participants
Very low

Adverse effects · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomes
short-term (up to 3 months)
SoF8: No included study reported the occurrence of adverse events.
0 studies
No studies found

Adverse effects · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomes
short-term (up to 3 months)
SoF6: No included study reported the occurrence of adverse events.
0 studies
No studies found