What do systematic reviews say?

Oral beta‐estradiol vs placebo

• Bioidentical hormones for women with vasomotor symptoms 2016 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 433 participants
  Low

Statin plus oral contraceptive pill vs oral contraceptive pill (OCP)

• Statins for women with polycystic ovary syndrome not actively trying to conceive 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2006 participants
  GRADE not reported

Combined oral contraceptive pill vs levonorgestrel intrauterine system

It is very uncertain whether combined oral contraceptive pill changes adverse effects ‐ Any adverse events compared with levonorgestrel‐releasing intrauterine system (very low certainty).

• Combined hormonal contraceptives for heavy menstrual bleeding 2019 · Cochrane Headline outcomes only
  OR 1.5 [0.22, 10.14]
  1 study · 39 participants
  Very low

Statins vs oral contraceptive pill plus flutamide

• Statins for women with polycystic ovary syndrome not actively trying to conceive 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2016 participants
  GRADE not reported

Transdermal oestrogens vs oral oestrogens

The review found no eligible studies for this question.

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found