Findings

What do systematic reviews say?

5 questions · 5 findings · 5 reviews · Oral Health

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No studies found 0 · 0%GRADE not reported 5 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Open surgical exposure vs Closed surgical exposure

Complications or adverse effects · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

1 finding from 1 review

Open versus closed surgical exposure of canine teeth that are displaced in the roof of the mouth 2017 · Cochrane All outcomes
Perioperative to alignment
SoF (Complications, no GRADE rating given): 'One surgical failure was due to detachment of the gold chain (closed group). One study reported two complications following surgery, both in the closed group: a…
1 study
GRADE not reported

Antioxidants (lycopene, curcumin, Oxitard) vs Placebo or no active treatment

Adverse effects · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)

1 finding from 1 review

Interventions for managing oral submucous fibrosis 2024 · Cochrane All outcomes
Adverse effects (any): 0 in placebo vs 2 minor (flatulence and bloating); 90 (1); no GRADE rating given.
1 study · 90 participants
GRADE not reported

Systemic beta carotene or carotenoids (incl. lycopene) vs placebo or no treatment

Safety of the intervention (adverse effects) · People with a diagnosis of oral leukoplakia

1 finding from 1 review

Interventions for treating oral leukoplakia to prevent oral cancer 2016 · Cochrane All outcomes
5 to 12 months
SoF 2, Safety of the intervention at 5 to 12 months: 'Systemic beta carotene did not cause any adverse effects in 1 study supplementing 10 mg/d (Nagao), and caused adverse effects of varying severity in 9% of…
3 studies
GRADE not reported

Repelling-magnet splints vs Bite-blocks

Side effects / adverse effects (unilateral crossbite; transverse problems) · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…

1 finding from 1 review

Orthodontic and orthopaedic treatment for anterior open bite in children 2014 · Cochrane All outcomes
About 4 months (treatment interrupted early)
"After 4 months the open bite was observed to close in the magnet group, but in four out of these ten patients, transverse problems were observed (unilateral crossbite) which led to the interruption of the treatment…
1 study · 10 participants
GRADE not reported

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

Post-operative adverse events and complications · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

1 finding from 1 review

Guided tissue regeneration for periodontal infra-bony defects 2006 · Cochrane All outcomes
Adverse effects were generally minor. Healing was generally uneventful for both test and control groups. Exposure of the GTR barrier membrane was widely reported, ranging from 20% of sites (non-resorbable…
16 studies
GRADE not reported