Findings

What do systematic reviews say?

3 questions · 3 findings · 3 reviews · Dental caries

No studies found 1 · 33.3%GRADE not reported 2 · 66.7%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Adverse effects · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience)

The review found no eligible studies for this question.

1 finding from 1 review

Water fluoridation for the prevention of dental caries 2015 · Cochrane All outcomes
No evidence to determine whether cessation of a water fluoridation programme is associated with any harms.
0 studies
No studies found

Adverse effects of toothpaste · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)

1 finding from 1 review

Fluoride toothpastes of different concentrations for preventing dental caries 2019 · Cochrane All outcomes
Closest to 36 months
16 studies assessed possible side effects, principally oral (soft tissue) pathologies and tooth staining. 6 studies reported no untoward events; 6 reported greater staining in the stannous fluoride group; 1 reported no…
16 studies
GRADE not reported

Adverse effects (loose stools, diarrhoea) · Infants (primary teeth; baseline about 9 to 15 months)

1 finding from 1 review

Xylitol‐containing products for preventing dental caries in children and adults 2015 · Cochrane All outcomes
12 months
Adverse effects were not reported in a usable format, but the reported rates of loose stools and diarrhoea were very similar between groups. There were no serious adverse effects during the study. Milgrom 2009.
1 study · 94 participants
GRADE not reported