Preventive interventions vs no preventive interventions
Adverse effects/events · Women at risk of postnatal psychosis
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
Findings
What do systematic reviews say?
16 questions · 16 findings · 4 reviews · Schizophrenia
No studies found 3 · 18.8%GRADE not reported 6 · 37.5%Very low 6 · 37.5%Low 1 · 6.3%Moderate 0 · 0%High 0 · 0%
Humour‐based interventions vs usual care
Adverse events as N of participants with at least one adverse event objective · patients with schizophrenia
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Humour‐based interventions vs active control
Adverse effects/events: at least 1 adverse effect ‐ as defined by individual studies. · patients with schizophrenia
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Group B antipsychotic drugs: amisulpiride + needs‐focused intervention vs needs‐focused intervention
Adverse effects: suicidal thoughts (events) · people in the prodromal stage of psychosis
It is very uncertain whether group B antipsychotic drugs: amisulpiride + needs‐focused intervention changes adverse effects: suicidal thoughts (events) compared with needs‐focused intervention (very low certainty).
1 finding from 1 review
- RR 0.25 [0.01, 6.1]1 study · 102 participantsVery low
Group B cognitive behavioural therapy: cognitive behavioural therapy + supportive therapy vs supportive therapy
Adverse effects: at least one serious adverse event · people in the prodromal stage of psychosis
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
Group B cognitive behavioural therapy: cognitive behavioural therapy (specific preventive intervention) + needs‐based intervention + risperidone vs needs‐based intervention
Adverse effects: at least one serious adverse event · people in the prodromal stage of psychosis
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
Group C cognitive behavioural therapy: cognitive behavioural therapy + supportive intervention vs non‐directive reflective listening + supportive intervention
Adverse effects: at least one serious adverse event · people in the prodromal stage of psychosis
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
Cognitive training vs active control
Adverse effects: at least one serious adverse event · people in the prodromal stage of psychosis
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
Group C other: integrated treatment vs usual care
Adverse effects: at least one serious adverse event · people in the prodromal stage of psychosis
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
Group A: amino acids vs placebo
Adverse effects: suicidal thoughts (events) · people in the prodromal stage of psychosis
It is very uncertain whether group A: amino acids changes adverse effects: suicidal thoughts Short‐term (events) compared with placebo (very low certainty).
1 finding from 1 review
- RR 3.57 [0.15, 83.14]1 study · 44 participantsVery low
Omega‐3 vs placebo
Adverse effects: neurological, extrapyramidal UKU (events) Medium‐term · people in the prodromal stage of psychosis
Group A: omega‐3 fatty acids showed no clear difference in adverse effects: neurological, extrapyramidal UKU (events) Medium‐term compared with placebo (low certainty).
1 finding from 1 review
- RR 2.57 [0.94, 7.02]1 study · 304 participantsLow
Group C cognitive behavioural therapy: cognitive behavioural therapy + risperidone vs placebo or supportive treatment
Adverse effects: specific ‐ doctors' assessment of adverse effects UKU (events) Medium‐term · people in the prodromal stage of psychosis
It is very uncertain whether group C cognitive behavioural therapy: cognitive behavioural therapy… changes adverse effects: doctors' assessment of adverse effects UKU (events)… compared with supportive therapy + placebo (very low certainty).
1 finding from 1 review
- RR 1.43 [0.64, 3.16]1 study · 58 participantsVery low
COGNITIVE REMEDIATION PROGRAMME (CRP) + PSYCHOEDUCATIONAL TREATMENT PROGRAMME (PTP) vs PTP (all medium‐term)
Adverse effect: clinically important adverse effect of intervention ‐ as defined by individual studies · Adolescents with psychosis
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Group B antipsychotic drugs: olanzapine + supportive intervention vs placebo or supportive treatment
Weight gain · people in the prodromal stage of psychosis
1 finding from 1 review
- no estimate extracted1 study · 59 participantsVery low
Group B cognitive behavioural therapy: cognitive behavioural therapy + risperidone vs placebo and cognitive and behavioural therapies
Adverse effects: specific ‐ doctors' assessment of adverse effects UKU (events) Medium‐term · people in the prodromal stage of psychosis
It is very uncertain whether group B cognitive behavioural therapy: cognitive behavioural therapy… changes adverse effects: specific ‐ doctors' assessment of adverse effects… compared with cognitive behavioural therapy + placebo (very low certainty).
1 finding from 1 review
- RR 1.03 [0.55, 1.91]1 study · 65 participantsVery low
Group C cognitive behavioural therapy: cognitive behavioural therapy + placebo vs placebo or supportive treatment
Adverse effects: specific ‐ doctors' assessment of adverse effects UKU (events) Medium‐term · people in the prodromal stage of psychosis
It is very uncertain whether group C cognitive behavioural therapy: cognitive behavioural therapy… changes adverse effects: specific ‐ doctors' assessment of adverse effects… compared with supportive therapy + placebo (very low certainty).
1 finding from 1 review
- RR 1.39 [0.61, 3.18]1 study · 51 participantsVery low