Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

272 questions · 272 findings · 91 reviews · Headline outcomes only

No studies found 107 · 39.3%GRADE not reported 15 · 5.5%Very low 57 · 21%Low 41 · 15.1%Moderate 45 · 16.5%High 7 · 2.6%

Pharmacological interventions vs placebo

Gastrointestinal adverse events · people with depression after stroke

It is very uncertain whether pharmacological interventions changes adverse events: all ‐ gastrointestinal effects (e.g. constipation,… compared with placebo (very low certainty).

1 finding from 1 review