Laser therapy vs no intervention
- Interventions for prevention of herpes simplex labialis (cold sores on the lips) 2015 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 119 participantsLow
It is very uncertain whether etretinate with PUVA therapy as co‐intervention changes proportion of participants with adverse effects ‐ measured over 20… compared with placebo with PUVA therapy (very low certainty).
The review found no eligible studies for this question.
Valaciclovir (short‐term) showed no clear difference in adverse effects during use of the preventative intervention compared with placebo (moderate certainty).
Valaciclovir (long‐term) showed no clear difference in adverse effects during use of the preventative intervention compared with placebo (moderate certainty).
It is very uncertain whether valaciclovir (suppressive regimen changes adverse effects during use of the preventative intervention compared with episodic regimen) (very low certainty).
Topical aciclovir (short‐term) showed no clear difference in adverse effects during use of the preventative intervention compared with placebo (low certainty).
Thymopentin showed no clear difference in adverse effects during use of the preventative intervention compared with placebo (moderate certainty).
HSV vaccination showed no clear difference in adverse effects during use of the preventative intervention compared with placebo (moderate certainty).
Yellow fever vaccination showed no clear difference in adverse effects during use of the preventative intervention compared with placebo (moderate certainty).
Interferon probably leads to higher adverse effects during use of the preventative intervention (fever)… compared with placebo (moderate certainty).
Interferon showed no clear difference in adverse effects during use of the preventative intervention (fever)… compared with placebo (moderate certainty).
Topical foscarnet showed no clear difference in adverse effects during use of the preventative intervention (leading… compared with placebo (moderate certainty).
Topical foscarnet showed no clear difference in adverse effects during use of the preventative intervention… compared with placebo (moderate certainty).
Oral aciclovir (short‐term) showed no clear difference in adverse effects during use of the preventative intervention ‐… compared with placebo (moderate certainty).
Oral aciclovir (short‐term) showed no clear difference in adverse effects during use of the preventative intervention ‐… compared with placebo (low certainty).
Interferon showed no clear difference in adverse effects during use of the preventative intervention (fever)… compared with placebo (moderate certainty).
Desloratadine 5 to 20 mg showed no clear difference in adverse effects leading to withdrawal: intermediate‐term duration of… compared with placebo (low certainty).