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What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 2 reviews · Acute Respiratory Infections

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Antibiotics vs placebo compared

Adverse effects of antibiotics · children, aged 2 to 59 months, with WHO‐defined non‐severe pneumonia and wheeze

Antibiotic therapy showed no clear difference in treatment harms (adverse events or side effects associated with… compared with placebo compared to placebo (low certainty).

1 finding from 1 review

Vitamin C vs placebo

Adverse effects (urticaria) Defined as participants reporting urticaria (hives) Dose: 2 g per day · school‐aged children (6 to 15 years) and marine corps recruits (mean age 18.5 years)

It is very uncertain whether vitamin C changes adverse effects (urticaria) Defined as participants reporting… compared with placebo (very low certainty).

1 finding from 1 review