Findings

What do systematic reviews say?

3 questions · 3 findings · 3 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 66.7%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%

Any prophylaxis vs no prophylaxis

Adverse effects · newborn children

It is very uncertain whether any prophylaxis changes adverse effects compared with no prophylaxis (very low certainty).

1 finding from 1 review

Interventions for preventing ophthalmia neonatorum 2020 · Cochrane Headline outcomes only
OR 0.93
1993 participants
Very low

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs placebo

Adverse effects · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…

It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes adverse effects compared with placebo (very low certainty).

1 finding from 1 review

Antibiotics to prevent complications following tooth extractions 2021 · Cochrane All outcomes
1st to 7th day
RR 1.46 [0.81, 2.64]
8 studies · 1277 participants
Very low

Prophylaxis with standard therapeutic factor concentrate vs pegylated liposome FVIII formulation

Any reported adverse effects · children or adults with hemophilia A

1 finding from 1 review

Clotting factor concentrates for preventing bleeding and bleeding‐related complications in previously treated… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 143 participants
Low