What do systematic reviews say?

Topical clobetasol propionate vs Topical ciclosporin

It is very uncertain whether topical clobetasol propionate changes adverse effects compared with topical ciclosporin (very low certainty).

• Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes

  3-8 weeks
  RR 6.32 [0.84, 47.69]
  1 study · 39 participants
  Very low

Topical corticosteroids vs placebo

It is very uncertain whether topical corticosteroid changes adverse effects compared with placebo (very low certainty).

• Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes

  3-9 weeks
  RR 1.48 [0.48, 4.56]
  3 studies · 88 participants
  Very low

Camouflage syringe vs Conventional syringe

The review found no eligible studies for this question.

• Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental treatment 2020 · Cochrane All outcomes

  During LA (injection is the intervention)
  Adverse effects: included studies did not report on this outcome
  Studies not reported
  No studies found

Video modelling acclimatisation for LA vs Oral hygiene video

The review found no eligible studies for this question.

• Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental treatment 2020 · Cochrane All outcomes

  In advance of LA
  Adverse effects: included studies did not report on this outcome
  Studies not reported
  No studies found

Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs High-content fluoride toothpaste (1350 ppm)

• Interventions for preventing osteoradionecrosis of the jaws in adults receiving head and neck radiotherapy 2019 · Cochrane All outcomes

  14 to 36 months
  Adverse effects were an outcome of interest in the study conducting this comparison, however no mention was made of the presence or absence of any adverse events
  1 study · 220 participants
  Very low

Ledermix root canal medicament (day 0 to 10) vs Ultracal root canal medicament (day 7 to 10)

• Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted 2019 · Cochrane All outcomes
  Day 2012 used a formal methodology to identify and report adverse effects, with none identified.
  1 study · 22 participants
  GRADE not reported

Extra-oral pulp extirpation at day 0 vs Intra-oral pulp extirpation at day 7

• Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted 2019 · Cochrane All outcomes
  Giannetti 2006 did not report this outcome; following email correspondence, authors reported no adverse effects were seen (uncertain whether formally assessed).
  1 study
  GRADE not reported

Hyperbaric oxygen therapy (HBO) following extractions vs penicillin G

• Interventions for preventing osteoradionecrosis of the jaws in adults receiving head and neck radiotherapy 2019 · Cochrane All outcomes

  6 months
  Adverse effects were an outcome of interest in the study conducting this comparison, however no mention was made of the presence or absence of any adverse events
  1 study · 74 participants
  Very low

Hyperbaric oxygen (following replantation) vs control

• Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted 2019 · Cochrane All outcomes
  Chen 2000 did not report this outcome; following email correspondence, authors reported no adverse effects were seen (uncertain whether formally assessed).
  1 study
  GRADE not reported

Thymosin alpha 1 (10-minute soak prior to replantation) vs Normal saline

• Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted 2019 · Cochrane All outcomes
  Loo 2008 did not report this outcome; following email correspondence, authors reported no adverse effects were seen (uncertain whether formally assessed).
  1 study
  GRADE not reported

Clinic‐based intervention vs usual care

The review found no eligible studies for this question.

• Disease management interventions for heart failure 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Multidisciplinary disease management programmes vs usual care

• Disease management interventions for heart failure 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 496 participants
  Moderate

Case management vs usual care

The review found no eligible studies for this question.

• Disease management interventions for heart failure 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pelvic floor muscle training (PFMT) with urotherapy vs urotherapy alone

The review found no eligible studies for this question.

• Conservative interventions for treating functional daytime urinary incontinence in children 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Voiding education with uroflow feedback and urotherapy vs urotherapy alone

• Conservative interventions for treating functional daytime urinary incontinence in children 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 133 participants
  GRADE not reported

Timer watch plus standard urotherapy vs urotherapy alone

The review found no eligible studies for this question.

• Conservative interventions for treating functional daytime urinary incontinence in children 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Transcutaneous electrical nerve stimulation (TENS) and standard urotherapy vs pelvic floor muscle training (PFMT) with electromyographic biofeedback and standard urotherapy

The review found no eligible studies for this question.

• Conservative interventions for treating functional daytime urinary incontinence in children 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pelvic floor muscle training (PFMT) with electromyography biofeedback and standard urotherapy vs pelvic floor muscle training without biofeedback but with standard urotherapy

The review found no eligible studies for this question.

• Conservative interventions for treating functional daytime urinary incontinence in children 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pelvic floor muscle training vs anticholinergics

• Conservative interventions for treating functional daytime urinary incontinence in children 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 47 participants
  Very low

TENS vs anticholinergics

• Conservative interventions for treating functional daytime urinary incontinence in children 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 61 participants
  Very low