Findings

What do systematic reviews say?

26 questions · 27 findings · 6 reviews

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No studies found 13 · 48.1%GRADE not reported 4 · 14.8%Very low 9 · 33.3%Low 0 · 0%Moderate 1 · 3.7%High 0 · 0%

Injectional verapamil vs saline (short‐term)

Treatment‐related adverse effects · men with Peyronie's disease (palpable plaque or pain)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

Injectional Botox vs placebo

Treatment‐related adverse effects · men with Peyronie's disease (stable phase)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Extracorporeal shockwave therapy vs sham

Treatment‐related adverse effects · men with Peyronie's disease (palpable plaque or pain)

It is very uncertain whether extracorporeal shock wave treatment (ESWT) changes treatment‐related adverse effects compared with sham (very low certainty).

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
RR 2.73 [0.74, 10.14]
3 studies · 166 participants
Very low

Penile traction therapy vs no treatment (short‐term)

Treatment‐related adverse effects · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 90 participants
Very low

Injectional betamethasone vs Normal saline

Treatment‐related adverse effects (long‐term) · men with Peyronie's disease (not defined)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Harms: non-serious adverse effects (headache, discomfort, loosening of temporary anchorage devices) · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances

Light vibrational forces (LVF) showed no clear difference in harms: non-serious adverse effects (headache, discomfort, loosening… compared with conventional orthodontic appliance treatment (placebo or no adjunct); GRADE not reported.

1 finding from 1 review

Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
RR 0.96 [0.32, 2.85]
1 study · 45 participants
GRADE not reported