What do systematic reviews say?

RISPERIDONE vs OLANZAPINE

• Risperidone for psychosis‐induced aggression or agitation (rapid tranquillisation) 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 29 participants
  Very low

RISPERIDONE vs QUETIAPINE

It is very uncertain whether RISPERIDONE changes adverse effects: movement disorders over 24 hours compared with OTHER ANTIPSYCHOTIC: c. QUETIAPINE (very low certainty).

• Risperidone for psychosis‐induced aggression or agitation (rapid tranquillisation) 2018 · Cochrane Headline outcomes only
  RR 1.67 [0.46, 6.06]
  1 study · 40 participants
  Very low

RISPERIDONE vs COMBINATION: a. RISPERIDONE + OXCARBAZEPINE

It is very uncertain whether RISPERIDONE changes adverse effects: movement disorders, over 24 hours compared with COMBINATION: a. RISPERIDONE + OXCARBAZEPINE (very low certainty).

• Risperidone for psychosis‐induced aggression or agitation (rapid tranquillisation) 2018 · Cochrane Headline outcomes only
  RR 1.59 [0.49, 5.14]
  1 study · 68 participants
  Very low

RISPERIDONE vs COMBINATION: b. RISPERIDONE + VALPROIC ACID

It is very uncertain whether RISPERIDONE changes adverse effects: movement disorders, over 24 hours compared with COMBINATION: b. RISPERIDONE + VALPROIC ACID (very low certainty).

• Risperidone for psychosis‐induced aggression or agitation (rapid tranquillisation) 2018 · Cochrane Headline outcomes only
  RR 0.75 [0.28, 2.03]
  2 studies · 122 participants
  Very low

ARIPIPRAZOLE (IM) vs haloperidol

It is very uncertain whether ARIPIPRAZOLE (IM) changes adverse effects: movement disorders ‐ EPS during 24 hours (only… compared with OTHER ANTIPSYCHOTIC: a. HALOPERIDOL (very low certainty).

• Aripiprazole (intramuscular) for psychosis‐induced aggression or agitation (rapid tranquillisation) 2018 · Cochrane Headline outcomes only
  RR 0.29 [0.12, 0.7]
  2 studies · 471 participants
  Very low