Findings

What do systematic reviews say?

5 questions · 5 findings · 2 reviews · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 80%Moderate 1 · 20%High 0 · 0%

Acute gout attacks · people with chronic gout

Allopurinol showed no clear difference in acute gout attacks compared with placebo (moderate certainty).

1 finding from 1 review

Allopurinol for chronic gout 2014 · Cochrane Headline outcomes only
RR 0.64 [0.12, 3.52]
1 study · 51 participants
Moderate

Acute gout attacks · people with chronic gout

Allopurinol showed no clear difference in acute gout attacks compared with benzbromarone (low certainty).

1 finding from 1 review

Allopurinol for chronic gout 2014 · Cochrane Headline outcomes only
RR 0.28 [0.01, 6.58]
1 study · 55 participants
Low

Acute gout attacks · people with chronic gout

Allopurinol 100‐300 mg daily showed no clear difference in acute gout attacks compared with febuxostat 80 mg daily (low certainty).

1 finding from 1 review

Allopurinol for chronic gout 2014 · Cochrane Headline outcomes only
RR 0.89 [0.71, 1.1]
3 studies · 1136 participants
Low

Acute gout attacks · people with chronic gout

Benzbromarone showed no clear difference in acute gout attacks compared with allopurinol (low certainty).

1 finding from 1 review

Uricosuric medications for chronic gout 2014 · Cochrane Headline outcomes only
RR 3.58 [0.15, 84.13]
1 study · 55 participants
Low

Acute gout attacks · people with chronic gout

Probenecid showed no clear difference in acute gout attacks compared with allopurinol (low certainty).

1 finding from 1 review

Uricosuric medications for chronic gout 2014 · Cochrane Headline outcomes only
RR 0.96 [0.53, 1.75]
1 study · 37 participants
Low