What do systematic reviews say?

Medication reconciliation interventions vs no medication reconciliation

Medication reconciliation probably leads to lower ADEs ( compared with no medication reconciliation (moderate certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  OR 0.38 [0.18, 0.8]
  3 studies · 1336 participants
  Moderate

Medication reconciliation interventions vs usual care

Medication reconciliation interventions showed no clear difference in ADEs compared with standard care (low certainty).

• Impact of medication reconciliation for improving transitions of care 2018 · Cochrane Headline outcomes only
  RR 1.09 [0.91, 1.3]
  4 studies · 1363 participants
  Low

Medication reconciliation interventions vs usual care

It is very uncertain whether medication reconciliation interventions changes PADEs compared with standard care (very low certainty).

• Impact of medication reconciliation for improving transitions of care 2018 · Cochrane Headline outcomes only
  RR 0.37 [0.09, 1.57]
  3 studies · 1253 participants
  Very low

Medication reconciliation: pharmacist vs other professionals

Medication reconciliation: pharmacist showed no clear difference in ADEs ( compared with other professionals (low certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  OR 1.34 [0.73, 2.44]
  3 studies · 2873 participants
  Low

Medication reconciliation: multimodal intervention vs usual care

It is very uncertain whether medication reconciliation: multimodal intervention changes potential ADEs ( compared with usual care (very low certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  RR 0.97 [0.86, 1.09]
  1648 participants
  Very low

Medication reconciliation by pharmacist: database‐assisted MR vs unassisted MR

Medication reconciliation by pharmacist: database‐assisted MR may leads to lower potential ADEs ( ≥ 1 per patient) ( compared with unassisted MR (low certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  OR 0.26 [0.1, 0.64]
  2 studies · 3326 participants
  Low

CPOE/CDSS vs control/paper‐based

It is very uncertain whether CPOE/CDSS changes ADEs ( compared with control/paper‐based (very low certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  OR 0.24 [0.04, 1.5]
  2 studies · 827 participants
  Very low

Improved CPOE/CDSS vs standard CPOE/CDSS

Improved CPOE/CDSS probably leads to lower ADEs ( compared with standard CPOE/CDSS (moderate certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  OR 0.82 [0.71, 0.94]
  2382 participants
  Moderate

Intervention not reported

• Interventions for reducing medication errors in children in hospital 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Intervention not reported

• Interventions for reducing medication errors in children in hospital 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

Intervention not reported

• Interventions for reducing medication errors in children in hospital 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

Intervention not reported

• Interventions for reducing medication errors in children in hospital 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Intervention not reported

• Interventions for reducing medication errors in children in hospital 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

CPOE/CDSS: prioritised vs non‐prioritised alerts

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 participants
  Low