Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

6 questions · 6 findings · 3 reviews · Musculoskeletal

No studies found 1 · 16.7%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 5 · 83.3%High 0 · 0%

Intervention not reported

ACR 50 American College of Rheumatology improvement criteria · patients with rheumatoid arthritis

The intervention probably leads to higher ACR 50 American College of Rheumatology improvement criteria (moderate certainty).

1 finding from 1 review

Intervention not reported

ACR50 American College of Rheumatology improvement criteria · participants with rheumatoid arthritis and with partial response to MTX

The intervention probably leads to higher ACR50 American College of Rheumatology improvement criteria (moderate certainty).

1 finding from 1 review

Intervention not reported

ACR50 American College of Rheumatology 50% improvement criteria · participants with rheumatoid arthritis and with a partial response to DMARDs

The intervention probably leads to higher ACR50 American College of Rheumatology 50% improvement criteria (moderate certainty).

1 finding from 1 review

Intervention not reported

Outcome: ACR50 ‐ American College of Rheumatology Improvement Criteria · participants with rheumatoid arthritis

The review found no eligible studies for this question.

1 finding from 1 review

Celecoxib vs placebo

Clinical improvement: American College of Rheumatology 20% improvement criteria (ACR20) · patients with rheumatoid arthritis

Celecoxib probably leads to higher clinical improvement: American College of Rheumatology 20%… compared with placebo (moderate certainty).

1 finding from 1 review

Celecoxib vs NSAIDs

Clinical improvement: American College of Rheumatology 20% improvement criteria (ACR20) · patients with rheumatoid arthritis

Celecoxib showed no clear difference in clinical improvement: American College of Rheumatology 20%… compared with traditional NSAIDs (moderate certainty).

1 finding from 1 review