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Evidence found and GRADE certainty

8 questions · 11 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 18.2%Low 2 · 18.2%Moderate 2 · 18.2%High 5 · 45.5%

rFSH vs urinary‐derived gonadotrophins

Ongoing pregnancy / live birth rate per woman · patients with ovarian stimulation in assisted reproductive technology cycles

rFSH showed no clear difference in live birth (or ongoing pregnancy) by urinary gonadotrophin compared with urinary gonadotrophins: primary analyses (high certainty).

4 findings from 1 review
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rFSH vs urinary‐derived gonadotrophins

OHSS by urinary gonadotrophin · patients with ovarian stimulation in assisted reproductive technology cycles

rFSH showed no clear difference in OHSS by urinary gonadotrophin compared with urinary gonadotrophins: primary analyses (high certainty).

1 finding from 1 review

Recombinant luteinizing hormone (rLH) combined with recombinant follicle‐stimulating hormone (rFSH) vs rFSH alone

Live birth rate · Women undergoing ovarian stimulation with gonadotrophins in IVF and ICSI procedures

It is very uncertain whether recombinant luteinizing hormone (rLH) combined with recombinant… changes live birth rate compared with rFSH alone (very low certainty).

1 finding from 1 review

Recombinant luteinizing hormone (rLH) combined with recombinant follicle‐stimulating hormone (rFSH) vs rFSH alone

OHSS · Women undergoing ovarian stimulation with gonadotrophins in IVF and ICSI procedures

Recombinant luteinizing hormone (rLH) combined with recombinant… showed no clear difference in OHSS incidence compared with rFSH alone (low certainty).

1 finding from 1 review

Recombinant luteinizing hormone (rLH) combined with recombinant follicle‐stimulating hormone (rFSH) vs rFSH alone

Ongoing pregnancy · Women undergoing ovarian stimulation with gonadotrophins in IVF and ICSI procedures

Recombinant luteinizing hormone (rLH) combined with recombinant… probably leads to higher ongoing pregnancy rate compared with rFSH alone (moderate certainty).

1 finding from 1 review

Recombinant luteinizing hormone (rLH) combined with recombinant follicle‐stimulating hormone (rFSH) vs rFSH alone

Miscarriage · Women undergoing ovarian stimulation with gonadotrophins in IVF and ICSI procedures

Recombinant luteinizing hormone (rLH) combined with recombinant… showed no clear difference in miscarriage rate compared with rFSH alone (moderate certainty).

1 finding from 1 review

Recombinant luteinizing hormone (rLH) combined with recombinant follicle‐stimulating hormone (rFSH) vs rFSH alone

Cancellation rate for low response · Women undergoing ovarian stimulation with gonadotrophins in IVF and ICSI procedures

Recombinant luteinizing hormone (rLH) combined with recombinant… showed no clear difference in cancellation rate for low response compared with rFSH alone (low certainty).

1 finding from 1 review

Recombinant luteinizing hormone (rLH) combined with recombinant follicle‐stimulating hormone (rFSH) vs rFSH alone

Cancellation rate for imminent OHSS · Women undergoing ovarian stimulation with gonadotrophins in IVF and ICSI procedures

It is very uncertain whether recombinant luteinizing hormone (rLH) combined with recombinant… changes cancellation rate for imminent OHSS compared with rFSH alone (very low certainty).

1 finding from 1 review