Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Drugs and Alcohol

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No studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

naltrexone vs placebo or no pharmacological treatment

retention and abstinence, all patients · patients with opioid dependence

naltrexone showed no clear difference in retention and abstinence, all patients compared with placebo or no pharmacological treatments; GRADE not reported.

1 finding from 1 review

Oral naltrexone maintenance treatment for opioid dependence 2011 · Cochrane Headline outcomes only
RR 1.43 [0.72, 2.82]
6 studies · 393 participants
GRADE not reported

naltrexone vs placebo or no pharmacological treatment

Abstinence · patients with opioid dependence

naltrexone showed no clear difference in abstinence at compared with placebo or no pharmacological treatments; GRADE not reported.

1 finding from 1 review

Oral naltrexone maintenance treatment for opioid dependence 2011 · Cochrane Headline outcomes only
RR 1.28 [0.8, 2.05]
3 studies · 116 participants
GRADE not reported

naltrexone vs placebo or no pharmacological treatment

Side effects · patients with opioid dependence

naltrexone showed no clear difference in side effects compared with placebo or no pharmacological treatments; GRADE not reported.

1 finding from 1 review

Oral naltrexone maintenance treatment for opioid dependence 2011 · Cochrane Headline outcomes only
RR 1.29 [0.54, 3.11]
4 studies · 159 participants
GRADE not reported