naltrexone vs placebo or no pharmacological treatment: Side effects
naltrexone showed no clear difference in side effects compared with placebo or no pharmacological treatments; GRADE not reported.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
naltrexone vs placebo or no pharmacological treatments side effects · patients with opioid dependence naltrexone showed no clear difference in side effects compared with placebo or no pharmacological treatments; GRADE not reported. Oral naltrexone maintenance treatment for opioid dependence (2011) · Cochrane Headline outcomes only | RR 1.29 [0.54, 3.11] | 4 studies · 159 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oral naltrexone maintenance treatment for opioid dependence 2011 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.