Findings

What do systematic reviews say?

4 questions · 4 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 75%Low 1 · 25%Moderate 0 · 0%High 0 · 0%

hCG vs GnRH agonist

Multiple pregnancy rate · women trying to conceive by intrauterine insemination

It is very uncertain whether hCG changes multiple pregnancy rate per pregnancy compared with gnRH‐a (very low certainty).

1 finding from 1 review

Synchronised approach for intrauterine insemination in subfertile couples 2014 · Cochrane Headline outcomes only
OR 0.15 [0.02, 1.38]
4 studies · 74 participants
Very low

hCG vs LH surge

Multiple pregnancy rate · women trying to conceive by intrauterine insemination

It is very uncertain whether hCG changes multiple pregnancy rate per pregnancy compared with LH surge (very low certainty).

1 finding from 1 review

Synchronised approach for intrauterine insemination in subfertile couples 2014 · Cochrane Headline outcomes only
OR 1.12 [0.17, 7.6]
2 studies · 42 participants
Very low

u‐hCG vs r‐hCG

Multiple pregnancy rate · women trying to conceive by intrauterine insemination

u‐hCG showed no clear difference in multiple pregnancy rate per pregnancy compared with r‐hCG (low certainty).

1 finding from 1 review

Synchronised approach for intrauterine insemination in subfertile couples 2014 · Cochrane Headline outcomes only
OR 0.99 [0.4, 2.47]
2 studies · 109 participants
Low

Human chorionic gonadotropin (hCG) injection vs no treatment

Multiple pregnancy rate · women trying to conceive by intrauterine insemination

It is very uncertain whether human chorionic gonadotropin (hCG) injection changes multiple pregnancy rate compared with no treatment (very low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 1.03 [0.22, 4.92]
1 study · 130 participants
Very low