Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 28.6%Low 5 · 71.4%Moderate 0 · 0%High 0 · 0%

All‐cause mortality · patients with initial treatment of HIV infection in antiretroviral‐naive individuals

It is very uncertain whether d4T changes mortality compared with AZT (very low certainty).

1 finding from 1 review

Clinical progression · patients with initial treatment of HIV infection in antiretroviral‐naive individuals

d4T showed no clear difference in clinical progression compared with AZT (low certainty).

1 finding from 1 review

Severe adverse events · patients with initial treatment of HIV infection in antiretroviral‐naive individuals

d4T showed no clear difference in severe adverse events compared with AZT (low certainty).

1 finding from 1 review

Virologic response · patients with initial treatment of HIV infection in antiretroviral‐naive individuals

d4T showed no clear difference in virologic response compared with AZT (low certainty).

1 finding from 1 review

Adherence/tolerability/retention · patients with initial treatment of HIV infection in antiretroviral‐naive individuals

d4T showed no clear difference in adherence/tolerability/retention compared with AZT (low certainty).

1 finding from 1 review

Immunologic response · patients with initial treatment of HIV infection in antiretroviral‐naive individuals

1 finding from 1 review

Drug resistance · patients with initial treatment of HIV infection in antiretroviral‐naive individuals

It is very uncertain whether d4T changes drug resistance compared with AZT (very low certainty).

1 finding from 1 review