What do systematic reviews say?

d4T vs AZT

d4T showed no clear difference in severe adverse events compared with AZT (low certainty).

• Stavudine or zidovudine in three‐drug combination therapy for initial treatment of HIV infection in… 2010 · Cochrane Headline outcomes only
  RR 1.17 [0.97, 1.4]
  9 studies · 1363 participants
  Low