Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

220 questions · 226 findings · 32 reviews

No studies found 70 · 31%GRADE not reported 51 · 22.6%Very low 39 · 17.3%Low 30 · 13.3%Moderate 29 · 12.8%High 7 · 3.1%

0.2% zinc sulphate toothpaste vs Placebo toothpaste (without zinc)

Volatile sulphur compounds (VSC), halimeter · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

0.2% zinc sulphate toothpaste led to lower volatile sulphur compounds (VSC) compared with placebo toothpaste (without zinc); GRADE not reported.

1 finding from 1 review

0.2% zinc sulphate toothpaste vs Placebo toothpaste (without zinc)

Dentist-reported organoleptic test (OLT) score (scale 0 to 5) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

It is very uncertain whether 0.2% zinc sulphate toothpaste changes dentist-reported organoleptic test (OLT) score (scale 0 to 5) compared with placebo toothpaste (without zinc) (very low certainty).

1 finding from 1 review

Zinc vs placebo; no treatment

Stunted after 6 months · the promotion of growth and prevention of infections in infants less than six months of age

Zinc supplementation showed no clear difference in stunted after 6 months compared with placebo; no treatment (moderate certainty).

1 finding from 1 review

Zinc vs placebo; no treatment

Wasted after 6 months · the promotion of growth and prevention of infections in infants less than six months of age

Zinc supplementation showed no clear difference in wasted after 6 months compared with placebo; no treatment (low certainty).

1 finding from 1 review

Polaprezinc vs Azulene oral rinse

Taste disturbance (severe, > 2 on 0-3 scale) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

Polaprezinc led to lower taste disturbance (severe, > 2 on 0-3 scale) compared with azulene oral rinse; GRADE not reported.

1 finding from 1 review

Polaprezinc vs Azulene oral rinse

Oral pain · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

Polaprezinc led to lower oral pain (severe, > 2 on 0-3 scale) compared with azulene oral rinse; GRADE not reported.

1 finding from 1 review

Polaprezinc vs Azulene oral rinse

Disability of oral intake · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

Polaprezinc showed no clear difference in disability of oral intake compared with azulene oral rinse; GRADE not reported.

1 finding from 1 review