Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

7 questions · 7 findings · 1 reviews · Headline outcomes only

No studies found 5 · 71.4%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 1 · 14.3%High 0 · 0%

Topical vitamin D derivative vs placebo

Proportion of participants with adverse effects ‐ measured over 8 weeks · chronic palmoplantar pustulosis

Topical vitamin D derivative showed no clear difference in proportion of participants with adverse effects ‐ measured over 8… compared with placebo (moderate certainty).

1 finding from 1 review

Topical vitamin D derivative vs placebo

Proportion of participants cleared or almost cleared ‐ · chronic palmoplantar pustulosis

Topical vitamin D derivative may leads to higher proportion of participants cleared or almost cleared in the short… compared with placebo (low certainty).

1 finding from 1 review