Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

134 questions · 143 findings · 12 reviews

No studies found 17 · 11.9%GRADE not reported 58 · 40.6%Very low 17 · 11.9%Low 26 · 18.2%Moderate 14 · 9.8%High 11 · 7.7%

Vitamin D compounds (supplementation) vs placebo or control

Parathyroidectomy · Adults with chronic kidney disease requiring dialysis

Meta-analysis of randomised trials of vitamin D supplementation for Parathyroidectomy: RR 0.82 (95% CI 0.05 to 12.47), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.

1 finding from 1 review

Vitamin D compounds (supplementation) vs placebo or control

Alkaline phosphatase · Adults with chronic kidney disease not requiring dialysis

Meta-analysis of randomised trials of vitamin D supplementation for Alkaline phosphatase: WMD -21.81 (95% CI -40.39 to 3.22), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.

1 finding from 1 review

Vitamin D compounds (supplementation) vs placebo or control

Risk of hyperphosphataemia · Adults with chronic kidney disease not requiring dialysis

Meta-analysis of randomised trials of vitamin D supplementation for Risk of hyperphosphataemia: RR 1.58 (95% CI 0.47 to 5.30), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.

1 finding from 1 review

Vitamin D compounds (supplementation) vs placebo or control

Bone pain · Adults with chronic kidney disease requiring dialysis

Meta-analysis of randomised trials of vitamin D supplementation for Bone pain: RR 0.29 (95% CI 0.03 to 2.63), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.

1 finding from 1 review

Vitamin A supplementation (200,000 to 400,000 IU) vs placebo or no treatment

Adverse effects on women: abdominal cramps · women in the postpartum period

Vitamin A supplementation (200,000 to 400,000 IU) showed no clear difference in maternal adverse effects after administration: abdominal pain compared with placebo or no treatment (low certainty).

1 finding from 1 review