Findings

What do systematic reviews say?

9 questions · 9 findings · 5 reviews

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No studies found 3 · 33.3%GRADE not reported 0 · 0%Very low 1 · 11.1%Low 3 · 33.3%Moderate 0 · 0%High 2 · 22.2%

Vitamin D vs placebo or no intervention

Severe PPH (≥ 1000 mL) · pregnant women and their infants..

Vitamin D supplementation may leads to lower maternal adverse events: severe postpartum haemorrhage compared with placebo or no intervention (low certainty).

1 finding from 1 review

Vitamin D supplementation for women during pregnancy 2019 · Cochrane Headline outcomes only
RR 0.68 [0.51, 0.91]
1 study · 1134 participants
Low

Vitamin D plus calcium vs placebo or no intervention

Maternal adverse events · pregnant women and their infants..

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin D supplementation for women during pregnancy 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin C vs placebo

Adverse events · adults and children with exercise‐induced bronchoconstriction/asthma

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin C for asthma and exercise‐induced bronchoconstriction 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin C vs placebo

Adverse events · people with asthma

1 finding from 1 review

Vitamin C for asthma and exercise‐induced bronchoconstriction 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 41 participants
Very low

Magnesium and vitamin E co‐supplementation vs placebo

Adverse events · people with diabetes and foot ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Nutritional interventions for treating foot ulcers in people with diabetes 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Neonatal vitamin A supplementation vs control

Vomiting · mortality and morbidity in term neonates

Neonatal vitamin A supplementation showed no clear difference in adverse events during first 48‐72 hours post supplementation ‐… compared with control (high certainty).

1 finding from 1 review

Neonatal vitamin A supplementation for the prevention of mortality and morbidity in term neonates in low and middle… 2017 · Cochrane Headline outcomes only
RR 1 [0.93, 1.07]
5 studies · 99582 participants
High

Neonatal vitamin A supplementation vs control

Adverse effects: diarrhoea 48 to 72 hours · mortality and morbidity in term neonates

Neonatal vitamin A supplementation showed no clear difference in adverse events during first 48‐72 hours post supplementation ‐… compared with control (low certainty).

1 finding from 1 review

Neonatal vitamin A supplementation for the prevention of mortality and morbidity in term neonates in low and middle… 2017 · Cochrane Headline outcomes only
RR 0.96 [0.81, 1.13]
5 studies · 102638 participants
Low

Neonatal vitamin A supplementation vs control

Adverse events during first 48‐72 hours post supplementation ‐ bulging fontanelle · mortality and morbidity in term neonates

Neonatal vitamin A supplementation leads to higher adverse events during first 48‐72 hours post supplementation ‐… compared with control (high certainty).

1 finding from 1 review

Neonatal vitamin A supplementation for the prevention of mortality and morbidity in term neonates in low and middle… 2017 · Cochrane Headline outcomes only
RR 1.53 [1.11, 2.11]
5 studies · 100256 participants
High

Summary of findings: oral vitamin E supplementation vs placebo or no treatment

Adverse events · adults and children with cystic fibrosis

Summary of findings: oral vitamin E supplementation showed no clear difference in adverse events compared with placebo or no treatment (low certainty).

1 finding from 1 review

Antioxidant supplementation for lung disease in cystic fibrosis 2019 · Cochrane Headline outcomes only
OR 1 [0.13, 7.94]
1 study · 38 participants
Low