Neonatal mortality · Women receiving supplements in pregnancy
It is very uncertain whether any intermittent iron regimen (with or without other vitamins and… changes neonatal death (within 28 days after delivery) compared with daily regimen (with same vitamins and minerals)‐infant outcomes (very low certainty).
1 finding from 1 review
Congenital anomalies (including neural tube defects) · Women receiving supplements in pregnancy
1 finding from 1 review
Maternal anaemia at term (Hb less than 110 g/L at 37 weeks' gestation or more) (ALL) · Women receiving supplements in pregnancy
It is very uncertain whether any intermittent iron regimen (with or without other vitamins and… changes maternal anaemia at term (Hb less than 110 g/L at 37 weeks'… compared with daily regimen (with same vitamins and minerals)‐maternal outcomes (very low certainty).
1 finding from 1 review
Iron deficiency at term (as defined by trialists, based on any indicator of iron status at 37 wk gestation or more) · Women receiving supplements in pregnancy
1 finding from 1 review
Maternal iron‐deficiency anaemia at term (Hb less than 110 g/L and at least 1 additional laboratory indicators at 37 weeks' gestation or more) · Women receiving supplements in pregnancy
It is very uncertain whether any intermittent iron regimen (with or without other vitamins and… changes maternal iron‐deficiency anaemia at term (Hb less than 110 g/L and… compared with daily regimen (with same vitamins and minerals)‐maternal outcomes (very low certainty).
1 finding from 1 review
Maternal death · Women receiving supplements in pregnancy
Any intermittent iron regimen (with or without other vitamins and… led to lower maternal death (death while pregnant or within 42 days of… compared with daily regimen (with same vitamins and minerals)‐maternal outcomes; GRADE not reported.
1 finding from 1 review
Spina bifida · health: non‐randomised studies
It is very uncertain whether wheat flour or wheat flour products fortified with folic acid plus… changes spina bifida compared with unfortified wheat flours or wheat flour products (not containing… (very low certainty).
1 finding from 1 review
RR 0.29 [0.16, 0.56]
8037 participants
Very low
Encephalocoele · health: non‐randomised studies
It is very uncertain whether wheat flour or wheat flour products fortified with folic acid plus… changes encephalocoele compared with unfortified wheat flours or wheat flour products (not containing… (very low certainty).
1 finding from 1 review
RR 0.26 [0.13, 0.56]
8037 participants
Very low
Fatal anencephaly · health: non‐randomised studies
It is very uncertain whether wheat flour or wheat flour products fortified with folic acid plus… changes fatal anencephaly compared with unfortified wheat flours or wheat flour products (not containing… (very low certainty).
1 finding from 1 review
RR 0.47 [0.21, 1.07]
8037 participants
Very low
Folate concentration Serum folate levels, measured between 6 and 12 months after entry to the study · health: non‐randomised studies
1 finding from 1 review
no estimate extracted
657 participants
Very low
Anaemia · health: non‐randomised studies
It is very uncertain whether wheat flour or wheat flour products fortified with folic acid plus… changes anaemia compared with unfortified wheat flours or wheat flour products (not containing… (very low certainty).
1 finding from 1 review
RR 0.87 [0.68, 1.11]
657 participants
Very low
Erythrocyte folate concentrations (nmol/L) · health outcomes
1 finding from 1 review
Folate concentration Serum folate levels, measured between 6 and 12 months after entry to the study · health outcomes
1 finding from 1 review
Anaemia · health outcomes
Wheat flour or wheat flour products fortified with folic acid plus… showed no clear difference in anaemia compared with unfortified wheat flours or wheat flour products (not containing… (low certainty).
1 finding from 1 review
Haemoglobin (g/dL) · health outcomes
1 finding from 1 review
Neural tube defects (All) · health: non‐randomised studies
It is very uncertain whether wheat flour or wheat flour products fortified with folic acid plus… changes neural tube defects (spina bifida, encephalocoele, anencephaly‐fatal… compared with unfortified wheat flours or wheat flour products (not containing… (very low certainty).
1 finding from 1 review
RR 0.32 [0.21, 0.48]
8037 participants
Very low
Ulcer healing · people with diabetes and foot ulcers
It is very uncertain whether magnesium and vitamin E co‐supplementation changes ulcer healing (absolute change in individual parameters of ulcer… compared with placebo (very low certainty).
3 findings from 1 review
Ulcer healing (absolute change in individual parameters of ulcer dimensions over time: mean (SD) cm wound width reduction · people with diabetes and foot ulcers
It is very uncertain whether magnesium and vitamin E co‐supplementation changes ulcer healing (absolute change in individual parameters of ulcer… compared with placebo (very low certainty).
1 finding from 1 review
Quality of life · people with diabetes and foot ulcers
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · people with diabetes and foot ulcers
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found