Meta-analysis of randomised trials of vitamin D supplementation for Cardiovascular disease: RR 0.95 (95% CI 0.86 to 1.05), not statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
Meta-analysis of randomised trials of vitamin D supplementation for Bone mineral density in lumbar spine, Healthy children: SMD 0.15 (95% CI -0.01 to 0.31), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
Meta-analysis of randomised trials of vitamin D supplementation for Fractures: hip, Men aged >65 years and postmenopausal women: RR 1.15 (95% CI 0.99 to 1.33), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
Meta-analysis of randomised trials of vitamin D supplementation for Birth length: WMD 0.97 (95% CI -0.41 to 2.34), not statistically significant. Umbrella review outcome-level evidence grade: Substantial effect unlikely.
Meta-analysis of randomised trials of vitamin D supplementation for Systolic blood pressure: WMD -2.39 (95% CI -5.7 to 0.9), not statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
Meta-analysis of randomised trials of vitamin D supplementation for Bone mineral density (Whole body / total), Healthy children: SMD 0.1 (95% CI -0.06 to 0.26), not statistically significant. Umbrella review outcome-level evidence grade: Substantial effect unlikely.
Meta-analysis of randomised trials of vitamin D supplementation for Bone mineral density in hip, Healthy children: SMD 0.06 (95% CI -0.18 to 0.29), not statistically significant. Umbrella review outcome-level evidence grade: Substantial effect unlikely.
Meta-analysis of randomised trials of vitamin D supplementation for Bone mineral density, Community-dwelling adults: WMD -0.9 (95% CI -2.10 to 0.40), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
Meta-analysis of randomised trials of vitamin D supplementation for Dental caries: RR 0.53 (95% CI 0.43 to 0.65), statistically significant. Umbrella review outcome-level evidence grade: Probable.
Meta-analysis of randomised trials of vitamin D supplementation for Insulin resistance (Diabetes): SMD 0.16 (95% CI -0.11 to 0.42), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
It is very uncertain whether summary of findings table ‐ Vitamin B12 supplementation changes maternal anaemia compared with placebo/no vitamin B12 supplementation (very low certainty).
Summary of findings table ‐ Vitamin B12 supplementation showed no clear difference in low birthweight (< 2500 g) compared with placebo/no vitamin B12 supplementation (low certainty).
Summary of findings table ‐ Vitamin B12 supplementation showed no clear difference in preterm birth (< 37 weeks) compared with placebo/no vitamin B12 supplementation (low certainty).
The review found no eligible studies for this question.
It is very uncertain whether neonatal vitamin A supplementation changes all‐cause infant mortality at 6 months: risk ratios based on… compared with control (very low certainty).
Neonatal vitamin A supplementation showed no clear difference in all‐cause infant mortality at 6 months: risk ratios based on… compared with control (high certainty).
Neonatal vitamin A supplementation showed no clear difference in all‐cause neonatal mortality: risk ratios based on cumulative risk… compared with control (high certainty).
Neonatal vitamin A supplementation leads to higher adverse events during first 48‐72 hours post supplementation ‐… compared with control (high certainty).