What do systematic reviews say?

Tricyclic antidepressants vs placebo

Tricyclic antidepressants (TCAs) may leads to higher CGI (response rate) ‐ desipramine and nortriptyline compared with placebo (low certainty).

• Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents 2014 · Cochrane Headline outcomes only
  OR 18.5 [6.29, 54.39]
  3 studies · 125 participants
  Low