Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

18 questions · 18 findings · 2 reviews · Headline outcomes only

No studies found 7 · 38.9%GRADE not reported 1 · 5.6%Very low 3 · 16.7%Low 7 · 38.9%Moderate 0 · 0%High 0 · 0%

Tricyclic antidepressants vs another medication

Treatment response (post‐treatment score on self report and clinician‐rated scales) · somatoform disorders in adults

Tricyclic antidepressants showed no clear difference in treatment response (post‐treatment score on self report and… compared with another medication (low certainty).

1 finding from 1 review

Tricyclic antidepressants vs placebo

Benzodiazepine discontinuation, end of intervention · adults who withdraw from chronic benzodiazepine use

It is very uncertain whether tricyclic antidepressants changes benzodiazepine discontinuation, end of intervention compared with placebo (very low certainty).

1 finding from 1 review