What do systematic reviews say?

Total or near‐total thyroidectomy vs subtotal thyroidectomy

• Total or near‐total thyroidectomy versus subtotal thyroidectomy for multinodular non‐toxic goitre in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1284 participants
  Moderate

Total or near‐total thyroidectomy vs subtotal thyroidectomy

Total or near‐total thyroidectomy probably leads to lower a)Goitre recurrence b)Re‐intervention due to goitre recurrence compared with subtotal thyroidectomy (moderate certainty).

• Total or near‐total thyroidectomy versus subtotal thyroidectomy for multinodular non‐toxic goitre in adults 2015 · Cochrane Headline outcomes only
  OR 0.05 [0.01, 0.21]
  3 studies · 1057 participants
  Moderate

Total or near‐total thyroidectomy vs subtotal thyroidectomy

Total or near‐total thyroidectomy showed no clear difference in adverse events: a) Permanent recurrent laryngeal nerve palsy b)… compared with subtotal thyroidectomy (low certainty).

• Total or near‐total thyroidectomy versus subtotal thyroidectomy for multinodular non‐toxic goitre in adults 2015 · Cochrane Headline outcomes only
  OR 1.28 [0.38, 4.36]
  4 studies · 1275 participants
  Low

Total or near‐total thyroidectomy vs subtotal thyroidectomy

Total or near‐total thyroidectomy showed no clear difference in thyroid cancer incidence compared with subtotal thyroidectomy (low certainty).

• Total or near‐total thyroidectomy versus subtotal thyroidectomy for multinodular non‐toxic goitre in adults 2015 · Cochrane Headline outcomes only
  OR 1.32 [0.81, 2.15]
  3 studies · 1134 participants
  Low

Total or near‐total thyroidectomy vs subtotal thyroidectomy

The review found no eligible studies for this question.

• Total or near‐total thyroidectomy versus subtotal thyroidectomy for multinodular non‐toxic goitre in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Total or near‐total thyroidectomy vs subtotal thyroidectomy

The review found no eligible studies for this question.

• Total or near‐total thyroidectomy versus subtotal thyroidectomy for multinodular non‐toxic goitre in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found