Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 100%High 0 · 0%

Serious adverse events · neuropathic pain (two studies found in painful diabetic neuropathy, and one in lumbar radiculopathy)

Topiramate 200 to 400 mg showed no clear difference in serious adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Topiramate for neuropathic pain and fibromyalgia in adults 2013 · Cochrane Headline outcomes only
RR 0.9 [0.6, 1.3]
1586 participants
Moderate