Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

21 questions · 22 findings · 2 reviews · Wounds

No studies found 9 · 40.9%GRADE not reported 0 · 0%Very low 8 · 36.4%Low 3 · 13.6%Moderate 2 · 9.1%High 0 · 0%

Topical antimicrobial agent vs an alternative topical antimicrobial agent

Resolution of infection · people with diabetes and foot ulcers

It is very uncertain whether one topical antimicrobial agent changes resolution of infection Up to 24 weeks' compared with an alternative topical antimicrobial agent (very low certainty).

1 finding from 1 review

Topical antimicrobial agent vs topical non‐antimicrobial agent

Time to complete healing

Topical antimicrobial agent showed no clear difference in time to complete wound healing (time to event data) (6 months) compared with topical non‐antimicrobial agent (moderate certainty).

2 findings from 1 review

Topical antimicrobial agents (non‐dressing) vs topical non‐antimicrobial agent

Proportion of wounds healed · people with diabetes and foot ulcers

It is very uncertain whether topical antimicrobial agents (non‐dressing) changes proportion of wounds healed Up to 24 weeks' compared with non‐antimicrobial topical agents (non‐dressing) (very low certainty).

1 finding from 1 review

Topical antimicrobial agents (non‐dressing) vs topical non‐antimicrobial agent

Resolution of infection · people with diabetes and foot ulcers

Topical antimicrobial agents (non‐dressing) showed no clear difference in resolution of infection Up to 24 weeks' compared with non‐antimicrobial topical agents (non‐dressing) (low certainty).

1 finding from 1 review